Groundbreaking. Disruptive. Scalable. Accessible.
Our Key Discovery.
Removing one gene empowers the immune system to see cancer...and eradicate it.
We've identified that knocking out a single gene among 22,000+ in a key cell type (Treg) triggers the permanent destruction of cancer cells. Since the 1970s, the O’Malley Lab has pioneered research on steroid receptor coactivators - SRCs: now known as the ‘master regulators’ of genetic function. With our cutting-edge technology and leading scientists at Baylor College of Medicine, we are at the forefront of translating this revolutionary science into real-world therapies.
Our Key Discovery.
Our Key Discovery.
Disrupting one gene empowers the immune system to see cancer and eradicate most solid tumors.
We've identified that knocking out a single gene among 22,000+ in a key cell type (Treg) triggers the permanent destruction of cancer cells. Since the 1970s, the O’Malley Lab has pioneered research on steroid receptor coactivators - SRCs: now known as the ‘master regulators’ of genetic function. With our cutting-edge technology and leading scientists at Baylor College of Medicine, we are at the forefront of translating this revolutionary science into real-world therapies.
Groundbreaking. Disruptive. Scalable. Accessible.
Pre-Clinical Results
Our pre-clinical trials have shown compelling results. In tests with 400+ tumor-bearing mice, CoRegen-engineered Tregs eradicated and prevented cancer with no toxicity or inflammation.
Award-Winning Science
CoRegen’s science won the prestigious 2023 Cozzarelli Prize, recognized as the top paper among 2,500 reviewed by the world’s leading scientists— a powerful validation of our work.
Best in Class Innovation
Our scientific team consists of pioneers in molecular endocrinology with over 700 publications. With three strong patents and additional filings, our therapy is protected across a broad range of applications.
Headed to Patients
We've partnered with the leading expert in cell manufacturing for the production of our proprietary therapy, positioning us for a 2025 IND filing for human trials.
No Toxicity
Our novel approach can treat multiple cancers more effectively, with no toxicity, inflammation, or off-target effects—delivering CoRegen-engineered cells while preserving existing immune cells.
The Patient Experience
Patient treatments will be done in an outpatient setting. Treg infusion can be administered in any well-equipped infusion center with only a single therapy treatment.
Bert W. O'Malley, MD
Inventor & Principal Scientist
Chancellor of Baylor College of Medicine
"Father of Molecular Endocrinology".
65+ International Awards & Prizes.
Steve Gorlin
Executive Chairman
40+ years of leadership in pharma and biotech, driving six companies to $1B+ valuations or acquisitions.
Shawn Tomasello
Chief Executive Officer
Biotech leader with 40+ years of experience and a key architect in the $11.9B Kite Pharma and $21B Pharmacyclics acquisitions.
Our Leadership
Powerful science backed by a world-class team of biotech & pharma leaders. The foremost minds in science have united under CoRegen’s mission to eliminate cancer once and for all.
Bert W. O'Malley, MD
Inventor & Principal Scientist
Chancellor of Baylor College of Medicine "Father of Molecular Endocrinology". 65+ International Awards & Prizes.
Steve Gorlin
Executive Chairman
40+ years of leadership in pharma and biotech, driving six companies to $1B+ valuations or acquisitions.
Shawn Tomasello
Chief Executive Officer &
Board Member
Biotech leader with 40+ years of experience and a key architect in the $11.9B Kite Pharma and $21B Pharmacyclics acquisitions.
Revolutionary science, life changing impact.
At CoRegen, we are harnessing groundbreaking scientific innovation to change the world forever. Our mission is clear: to eradicate cancer and transform lives on a global scale. With every breakthrough, we move closer to a future where cancer is no longer a life-altering diagnosis.
Revolutionary science, life changing impact.
At CoRegen, we are harnessing groundbreaking scientific innovation to change the world forever. Our vision is clear: to eradicate cancer and transform lives on a global scale. With every breakthrough, we move closer to a future where cancer is no longer a life-altering diagnosis.
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